Focused flow droplet generator - topconnect

As low as €490.00
In stock

Pack of 3 focused flow droplet generators for use in combination with our Fluidic Connect Pro chip holder. The chips are available with a hydrophobic coated or an uncoated (hydrophilic) channel surface.

Indicated reference droplet sizes are based on a reference experiment with Silicone oil 5cSt and DI water combined with 2% v/v Tween 20 or Tween 80.

Pack of 3 single nozzle droplet generators with a nozzle etched on both sides, giving the following advantages:

  • Optimized nozzle geometry
  • Symmetric channels and nozzles for uniform droplet formation 
  • Droplet production stable over a broader size and frequency range
  • Smaller droplet sizes available

This microfluidic droplet generator is an excellent tool for generating highly reproducible microsized droplets with much higher precision and repeatability compared to conventional methods.

By tuning the relative viscosities, surface tension, and velocities between the dispersed and the continuous phase, droplet size and frequency can be altered. Oil-in-Water (O/W) droplets can be generated directly using the glass chips. Also, these droplet generators are suitable for coating in order to form Water-in-Oil droplets (W/O).

Further specifics:

  • Droplet size can roughly be tuned from the size of the nozzle to be doubled
  • Suitable for foam, digital PCR, single cell analysis, emulsions etc.
  • Made from high quality glass, borosilicate, suitable for most biological and chemical applications

Application examples:

Cell, DNA, bead encapsulation for

  • drug discovery
  • drug studies
  • molecular biological studies
  • immunology studies
  • evolutional studies
  • enzyme catalysis studies

Food, paints, foams

  • Bubble formation
  • Mineral Oil Emulsion Production
  • Particle production - PLGA, PEGDA, gelatine, alginate, polystyrene, agaros
  • Drug delivery - creams, aerosols


  • Droplet based micromixing
  • Droplet based microreactions
More Information
Unit of measurement3-Pack
Interface typeTopconnect
Chip materialBorosilicate glass
Supply format & dimensions

Supplied in a black polymer cardtridge with an external dimension of 75 x 25mm.
The functional glass element has a size of 45x15mm.

Chip thickness1800µm
Channel locationDepending on selection
Channel widthDepending on selection
Channel heightDepending on selection
Number of inlets2
Number of outlets1
Icon Label Description Type Size Download
pdf DGFF.10 - Drawing Drawing 10µm Focused Flow Droplet Generator pdf 159 KB Download
PDF DGFF.50 - Drawing PDF 179.6 KB Download
PDF DGFF.75 - Drawing PDF 193.6 KB Download
pdf Surface wetting properties pdf 220.3 KB Download
pdf Flow rate instructions pdf 303.6 KB Download
pdf Using the right surfactants pdf 168.8 KB Download
pdf How to prevent clogging pdf 153 KB Download
pdf Droplet Generator Guide pdf 617 KB Download
Customer Questions
How do I clean my chips?

One simple but very effective way to clean a microchip is to flush an alkaline solution through the channels. A solution of 1 M sodium hydroxide in water works well, but a lower concentration might also be sufficient. If traces of the cleaning solution...

I need a pumping system for my setup. Which one do you recommend?

We recommend using a high precision pumping system. Regular syringe pumps often don't work very well for droplet generators. There are several high precision pumping systems on the market that work with different pumping principles.

To name one, we'd like to mention that we have had positive experiences with the equipment Fluigent offers:


Which flowrates should I use?

This depends on many things. For example on the type of fluid that you are using. Check our flowrate instructions to find out how to start.

I only see streaks of fluids but no droplets. How do I get the droplets?

Decrease your flowrate. Check our flowrate instructions for a more acurate explanation.

Which surfactants should I use?

Use our surfactant guide for advice on surfactants.

How do I prevent clogging of my chips?

Have a look at our clogging prevention guide.

Should I use coated or uncoated droplet generators?

Have a look at our article about surface wetting properties.

Publication: Controlled and tunable polymer particles' production using a single microfluidic device

Amoyav, Benzion, and Ofra Benny "Controlled and tunable polymer particles’ production using a single microfluidic device." Applied Nanoscience (2018): 1-10. Abstract Microfluidics technology offers a new platform to control liquids under flow in small...

Publication: Spatiotemporal variation of endogenous cell-generated stresses within 3D multicellular spheroids

Lucio, Adam A., et al. "Spatiotemporal variation of endogenous cell-generated stresses within 3D multicellular spheroids." Scientific reports 7.1 (2017): 12022. Abstract Multicellular spheroids serve as an excellent platform to study tissue behavior...

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