Classic focused flow droplet generator
Classic droplet generator. The channels have half semi-oval shape.
Droplet generation is a important technique for emulsification and single cell encapsultation. Also in Pharmaceutical applications, droplet generation can play an important role in drug delivery, when active ingredients are mixed with biological polymers.
Micornit offers currently two versions of single junction focused flow droplet generators, we offer a "classic" and a new generation version. In most case the new generation droplet generators are the prefered choice. However the classic version helps to determine if a half semi-oval channel shape can be sufficient as this is relatively cost effective design. Because it's was one of the first commercial availble droplet generatore chips it's also referenced in a large amount of publications.
Half semi-oval channel shape ("classic") Full semi-oval channel shape ("new generation")
The "classic" droplet generator is available in the following configurations:
More details are displayed when the desired configuration is selected.
|Unit of measurement||3-Pack|
|Chip material||Borosilicate glass|
One simple but very effective way to clean a microchip is to flush an alkaline solution through the channels. A solution of 1 M sodium hydroxide in water works well, but a lower concentration might also be sufficient. If traces of the cleaning solution...
We recommend using a high precision pumping system. Regular syringe pumps often don't work very well for droplet generators. There are several high precision pumping systems on the market that work with different pumping principles.
To name one, we'd like to mention that we have had positive experiences with the equipment Fluigent offers: https://www.fluigent.com/
This depends on many things. For example on the type of fluid that you are using. Check our flowrate instructions to find out how to start.
Decrease your flowrate. Check our flowrate instructions for a more acurate explanation.
Use our surfactant guide for advice on surfactants.
Have a look at our article about surface wetting properties.
Amoyav, Benzion, and Ofra Benny "Controlled and tunable polymer particles’ production using a single microfluidic device." Applied Nanoscience (2018): 1-10. Abstract Microfluidics technology offers a new platform to control liquids under flow in small...
Lucio, Adam A., et al. "Spatiotemporal variation of endogenous cell-generated stresses within 3D multicellular spheroids." Scientific reports 7.1 (2017): 12022. Abstract Multicellular spheroids serve as an excellent platform to study tissue behavior...