We recommend using a high precision pumping system. Regular syringe pumps often don't work very well for droplet generators. There are several high precision pumping systems on the market that work with different pumping principles.
To name one, we'd like to mention that we have had positive experiences with the equipment Fluigent offers: https://www.fluigent.com/
This depends on many things. For example on the type of fluid that you are using. Check our flowrate instructions to find out how to start.
Decrease your flowrate. Check our flowrate instructions for a more acurate explanation.
Use our surfactant guide for advice on surfactants.
Have a look at our clogging prevention guide.
Have a look at our article about surface wetting properties.
Amoyav, Benzion, and Ofra Benny. "Controlled and tunable polymer particles’ production using a single microfluidic device." Applied Nanoscience (2018): 1-10.
Lucio, Adam A., et al. "Spatiotemporal variation of endogenous cell-generated stresses within 3D multicellular spheroids." Scientific reports 7.1 (2017): 12022.