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3-Pack F.F. Droplet (nozzle: 75 µm) (sideconnect)

Availability: In stock

Microfluidic droplet generators are excellent tools for generating highly reproducible microsized droplets with much higher precision and repeatability compared to conventional methods.


Pack of 3 single nozzle droplet generators with nozzle etched on both sides, giving the following advantages:

  • Optimised nozzle geometry
  • Symmetric channels and nozzles for uniform droplet formation 
  • Droplet production stable over a wider size and frequency range
  • Smaller droplet sizes available

This microfluidic droplet generator is an excellent tool for generating highly reproducible microsized droplets with much higher precision and repeatability compared to conventional methods.

By tuning the relative viscosities, surface tension, and velocities between the dispersed and the continuous phase, droplet size and frequency can be altered. Two versions of this chip are available, A chip for oil-in-water (O/W) droplets and a chip for water-in-oil droplets. The chips for oil-in-water have an untreated glass surface that is hydrophilic and the water-in-oil chips have an extra coating making them hydrophobic.


This droplet generator has the same functionality as our top-connected droplet generator with the same nozzle size. This version has the following advantages compared to the top connect version:

  • The chip and holder require less space in your setup
  • The chip and holder together weigh less than 5 grams.
  • The fluids stay in the same plane when entering the chip.
  • The system can handle higher pressures

A disadvantage of this holder is that it is slightly less convenient to connect and disconnect chips into the holder. Therefore, if the mentioned advantages are not relevant to you, choose the top-connected droplet generators

Further specifics:

  • Nozzle size 75 µm
  • Droplet size can roughly be tuned from the size of the nozzle to double this size
  • Suitable for foam, digital PCR, single cell analysis, emulsions etc.
  • Made from high quality glass, borosilicate, suitable for most biological and chemical applications.

Application examples:

Cell, DNA, bead encapsulation for

  • drug discovery
  • drug studies
  • molecular biological studies
  • immunology studies
  • evolutional studies
  • enzyme catalysis studies.

Food, paints, foams

  • Bubble formation
  • Mineral Oil Emulsion Production
  • Particle production - PLGA, PEGDA, gelatine, alginate, polystyrene, agaros
  • Drug delivery - creams, aerosols


  • Droplet based micromixing
  • Droplet based microreactions
Product CodeFF_DROP_SC_75
Product reference for order

Please use the following product references for an order:
- Uncoated (hydrophilic) chips:  01368
- Coated (hydrophobic) chips: 01641

Number of chips per pack3
Distance between channel and top surface638 µm
Distance between channel and bottom surface638 µm
Channel locationTop and bottom
Total chip thickness1400 µm
Chip size15 mm x 15 mm
Channel widthVaries
Channel height125 µm
Internal Volume1.6 µl
Nozzle height75 µm
Number of Inlets3 (2 inlet are used for continuous phase)
Number of outlets1
Optical propertiesOptical clear view from all sides
CoatingDepend on selection
Material chipBorosilicate glass

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How do I clean my chips?

One simple but very effective way to clean a microchip is to flush an alkaline solution through the channels. A solution of 1 M sodium hydroxide in water works well but a lower concentration might also be sufficient. If traces of the cleaning solution remaining inside the chip after cleaning and rinsing with water pose a problem then ammonia can be used instead. Note that these solutions are caustic and can cause damage to e.g. the polyimide coating of fused silica capillaries. Also plastic parts should not be exposed to very alkaline solutions.

In order to aid in the removal of particulate matter, a water bath with ultrasonic agitation can be used, preferably while flushing a watery solution through the channels using a Fluidic connect kit.

Glass microchips can be heated (e.g. >400° C) causing any organic material adsorbed on the glass surface to degrade. Try to use lower temperatures first because burning the content could make it stick. Make sure you only heat the glass chip and not the plastic parts around it.

Concentrated sulphuric acid works well to dissolve organic material such as fibres which are difficult to remove with alkaline solutions, but because of the extremely corrosive nature of the material a cleaning procedure is not so easily implemented.

Please note that chips that were coated by Micronit have different guidelines for cleaning.

What flowrates should I use?

This depends on many things, for example, which fluids you use. Check our flowrate instructions to find out how to start.

I only see streaks of fluids but no droplets, how do I get the droplets?

Decrease your flowrate. Check our flowrate instructions for a more acurate explanation.

Which surfactants should I use?

Have a look at our surfactant guide.

My chips are clogged, how do I prevent this?

Have a look at our clogging prevention guide

Should I use coated or uncoated droplet generators?

Have a look at our document about surface wetting properties.

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