Serpentine channel

SKU
serpentine_config
Availability:
In stock
As low as €236.00

per pack of 3

Flow cell with a serpentine channel. Details depend on selected configuration.

Application possibilities

This product is designed for observation purposes and offers sublime optical performance in combination with microscopy. This allows high resolution imaging. A regular flow cell offers a limited observation length, using a serpentine shaped channel substantial channel length is created. This allow much longer observation time without reducing the speed to much.  

Research examples can be for instance:

  • Observation of cell interaction with media, like for instance exposure to toxins or active substances.
  • Research on interaction between liquids
  • Observation of a reaction
  • Use as collection reservoir, for instance combined with a PCR reactions

Unique selling point

  • The channels doesn’t have any substantial roughness and are fully optical transparent due to the etching process used.
  • Glass offers sublime optical transparency and low autofluorescence.
  • When fluorescent markers are used we have also a D263-Bio version available for even lower autofluorescence in some critical wave length areas.
  • Thin bottom version are compatible with a #1 (11003694) or #1.5 (11003040) coverslip
  • Different size available for a optimal match with cell size used or optimal liquid volume.

Key features of the products 

SKU Number of inlets Number of outlets Channel width Max. cell diameter for optimal observation Channel height Glass height on top of channel Glass height below channel Chip height Glass
11003694 2 1 50µm 10µm 20µm 1100µm 145µm 1245µm D263
11003040 3 1 140µm 40µm 45µm 1100µm  175µm 1275µm D263Bio
11003033 3 1 250µm 110µm 140µm 830µm  830µm 1800µm D263

 

More Information
Unit of measurementpack of 3
Interface typeTopconnect
Chip materialBorosilicate glass
Icon Label Description Type Size Download
pdf 11003040 - Drawing Serpentine 45x140µm, 350mm, TB pdf 76.9 KB Download
pdf 11003033 - Drawing Serpentine 140x250µm, 500mm pdf 94.2 KB Download
pdf 11003694 / 11003694 / R50.332.3 - Drawing Serpentine 20x50µm, 342mm pdf 79.1 KB Download
Customer Questions
Can this flow cell be customized?
Absolutely! Micronit is a key supplier for flow cells in the Next Generation Sequencing market and can manufacture flow cells competely according to your specific requirements.  What can be customized?

The channel shape. The channel height and width.
For wet etching its important to consider that channel height and minimal channel width are related.
{minimal channel width} = 2 * {etch depth} + {initial mask opening, typcial 5-10µm} 
Larger aspect ratios (relation between channel depth and width) are possible using dry etching. For this, a glass/silicon combination is most common. Choice of material. For instance, fused silica is a good option when UV light is used. Schott D263 bio can be a good alternative for some specific fluorescent labels.  Surface flatness. We can provide ultra flat surfaces.
When should I use the metal strips (spacers) as provided with the Fluidic Connect Pro holder?
When should I use the spacers? The metal strips are used for thin bottom chips and are also part of the holder for resealable flow cell's.
This are currently the following products (list might be incomplete): SKU Description Note 00746 Fluidic Connect Pro for resealable flow cells Normally already pre-assembled  00745 Insert set for resealable flow cells   03133 Thin bottom flow cell    03133-F Thin bottom flow cell - coated   03196 Thin bottom flow cell - 0.5mm   03196-F Thin bottom flow cell - 0.5mm - coated   03164 Thin bottom flow cell - 1.5mm   03164-F Thin bottom flow cell - 1.5mm - coated   FC_R50.332.3_PACK Serpentine channel / Microreactor, 20x50µm, 342mm length   FC_R50.332.3-F Serpentine channel / Microreactor, 20x50µm, 342mm length - Coated   03040 Serpentine channel / Microreactor, 45x140µm, 350mm length   03040 - F 03040Serpentine channel / Microreactor, 45x140µm, 350mm length - coated   FC_X3550CH.3_PACK Cross channel chip - thin bottom   How to apply the spacers? The spacers are placed beneath the top insert, as shown in the picture below. What should I do when I don't have spacers available?
Just contact us to request new spacers.
What is the roughness of the etched structures?
Wet etched structures are extremely smooth and have a roughness in Angstrom range. The structures are fully optical transparent. 
Large roughness for structures in glass chips is typical observed for structures manufactured by use of laser assisted manufacturing techniques or abrasion-based techniques like powder blasting. Almost all catalogue products from Micronit are manufactured using wet etching to create full transparent channels without substantial roughness. 
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